106351-99-9 Usage
Chemical derivative
2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]-4-phosphono-butanoic acid is a chemical compound that is a derivative of folic acid.
Role in biosynthesis
It is an important intermediate in the biosynthesis of tetrahydrofolate, a coenzyme involved in the transfer of one-carbon units in the synthesis of purines, thymidylate, and certain amino acids.
Phosphonic acid group
It has a phosphonic acid group, which makes it a potential inhibitor of dihydrofolate reductase, an enzyme involved in the de novo synthesis of purines and thymidylate.
Importance in pharmaceuticals
Its structure and function make it important in the development of pharmaceuticals for the treatment of cancer and other diseases related to folate metabolism.
Check Digit Verification of cas no
The CAS Registry Mumber 106351-99-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,3,5 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 106351-99:
(8*1)+(7*0)+(6*6)+(5*3)+(4*5)+(3*1)+(2*9)+(1*9)=109
109 % 10 = 9
So 106351-99-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H21N8O6P/c19-14-13-15(26-18(20)25-14)22-8-11(23-13)7-21-10-3-1-9(2-4-10)16(27)24-12(17(28)29)5-6-33(30,31)32/h1-4,8,12,21H,5-7H2,(H,24,27)(H,28,29)(H2,30,31,32)(H4,19,20,22,25,26)
