106362-34-9 Usage
Uses
Used in Pharmaceutical Industry:
(D-ALA1)-PEPTIDE T AMIDE is used as a chemokine receptor 5 (CCR5) antagonist for its selective viral entry inhibition properties against R5 tropic HIV-1 strains. By blocking CCR5-mediated monocyte chemotaxis, it can potentially play a role in the development of antiviral therapies and treatments.
Used in Research and Development:
In the field of research, (D-ALA1)-PEPTIDE T AMIDE can be utilized as a valuable tool for studying the interactions between chemokine receptors and their ligands. This can lead to a better understanding of the underlying mechanisms of various diseases and the development of targeted therapies.
Used in Drug Design and Development:
The unique properties of (D-ALA1)-PEPTIDE T AMIDE make it a promising candidate for the design and development of new drugs targeting chemokine receptors. Its ability to selectively inhibit CCR5 can be exploited to create novel therapeutic agents for the treatment of HIV and other related conditions.
Used in Diagnostic Applications:
(D-ALA1)-PEPTIDE T AMIDE can also be employed in the development of diagnostic tools and assays to detect the presence of specific chemokine receptors or their interactions with other molecules. This can aid in the early detection and monitoring of diseases associated with these receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 106362-34-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,3,6 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 106362-34:
(8*1)+(7*0)+(6*6)+(5*3)+(4*6)+(3*2)+(2*3)+(1*4)=99
99 % 10 = 9
So 106362-34-9 is a valid CAS Registry Number.
InChI:InChI=1/C35H56N10O15/c1-13(36)29(54)41-22(12-46)32(57)43-26(16(4)49)34(59)45-27(17(5)50)35(60)44-25(15(3)48)33(58)40-21(11-23(37)52)30(55)39-20(10-18-6-8-19(51)9-7-18)31(56)42-24(14(2)47)28(38)53/h6-9,13-17,20-22,24-27,46-51H,10-12,36H2,1-5H3,(H2,37,52)(H2,38,53)(H,39,55)(H,40,58)(H,41,54)(H,42,56)(H,43,57)(H,44,60)(H,45,59)/t13-,14-,15-,16-,17-,20+,21+,22+,24+,25+,26+,27+/m1/s1
106362-34-9Relevant academic research and scientific papers
CONTINUOUS-FLOW SOLID-PHASE PEPTIDE SYNTHESIS
Krchnak, Viktor,Vagner, Josef,Flegel, Martin,Mach, Otakar
, p. 4469 - 4472 (2007/10/02)
We describe a simple manually operated synthesizer for solid-phase peptide synthesis (SPPS).The synthesis is performed on standard polystyrene-based resin in a flow reactor under low-pressure conditions.The usefulness of the present configuration of SPPS is exemplified on the synthesis of two octapeptide and one decapeptide amides.
