1063627-02-0Relevant articles and documents
A rapid and facile synthesis of new spiropyrimidines from 5-(2-arylethylidene-2-oxo)-1,3-dimethylpyrimidine-2,4,6-triones
Gozalishvili, Lali L.,Beryozkina, Tetyana V.,Omelchenko, Irina V.,Zubatyuk, Roman I.,Shishkin, Oleg V.,Kolos, Nadezhda N.
, p. 8759 - 8765 (2008)
A series of new tetraazaspiro[5,5]-undec-4-ene-2,7,9,11-tetraones have been obtained by reaction of 5-(2-arylethylidene-2-oxo)-1,3-dimethylpyrimidine-2,4,6-triones with ureas. A three-component one-pot procedure to the spiranes synthesis was also developed. One-pot reaction of arylglyoxals, 1,3-dimethylbarbituric acid, and dimethylurea led to imidazolyl-1,3-dimethylbarbituric acids. Mechanisms of studied reactions were discussed.