1063709-23-8Relevant articles and documents
Highly Enantioselective Cobalt-Catalyzed (3+2) Cycloadditions of Alkynylidenecyclopropanes
Da Concepción, Eduardo,Fernández, Israel,Mascare?as, José L.,López, Fernando
supporting information, p. 8182 - 8188 (2021/03/16)
Low-valent cobalt complexes equipped with chiral ligands can efficiently promote highly enantioselective (3+2) cycloadditions of alkyne-tethered alkylidenecyclopropanes. The annulation allows to assemble bicyclic systems containing five-membered rings in good yields and with excellent enantiomeric ratios. We also present a mechanistic discussion based on experimental and computational data, which support the involvement of CoI/CoIII catalytic cycles.