106376-18-5

Basic information

• Product Name: N-phenyl-3-(trifluoromethyl)benzamide
• Synonyms: N-phenyl-3-(trifluoromethyl)benzamide
• CAS NO: 106376-18-5
• Molecular Formula: C₁₄H₁₀F₃NO
• Molecular Weight: 265.2305096
• Mol File: 106376-18-5.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-phenyl-3-(trifluoromethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-3-(trifluoromethyl)benzamide(106376-18-5)
• EPA Substance Registry System: N-phenyl-3-(trifluoromethyl)benzamide(106376-18-5)

Safety Data

• Hazardous Substances Data: 106376-18-5(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 401-81-0 m-trifluoromethylphenyl iodide 
• 62-53-3 aniline 
• 98-80-6 phenylboronic acid 
• 3422-02-4 N-(benzyloxycarbonyl)aniline 
• 3422-01-3 tert-butyl phenylcarbamate 
• 18992-89-7 allyl N-phenylcarbamate 
• 103-71-9 phenyl isocyanate 
• 76783-59-0 ethyl 3-(trifluoromethyl)benzoate 
• 723252-38-8 C₁₄H₉ClF₃NO 
• 98-95-3 nitrobenzene 
• 58710-61-5 phenyl 3-(trifluoromethyl)benzoate 
• 368-77-4 3-trifluoromethylbenzonitrile 
• 591-50-4 iodobenzene 

Downstream Products

• 350487-59-1 N'-methoxy-N-phenyl-3-(trifluoromethyl)benzimidamide 
• 1609460-47-0 1-benzyl-2-(3-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole 
• 1609460-29-8 N-benzyl-N'-phenyl-3-(trifluoromethyl)benzimidamide 
• 1372890-84-0 4-phenyl-2-(3-(trifluoromethyl)phenyl)quinazoline 
• 425366-00-3 N-phenyl-3-trifluoromethyl-benzimidic acid 4-cyano-phenyl ester 
• 425366-16-1 phenyl-(3-trifluoromethyl-phenylmethylidyne)-ammonium 

Relevant articles and documents

Role of intermolecular interactions involving organic fluorine in trifluoromethylated benzanilides

Trifluoromethylated benzanilides, containing C(sp3)-F bonds, have been synthesized and their crystal and molecular structures have been investigated to highlight the significance of weak intermolecular interactions associated with the presence

Exploration of Cu-catalyzed regioselective hydrodehalogenation of o-haloanilides using EtOH as hydrogen source

In present work, we have explored a Cu(acac)2/vasicine-catalyzed regioselective hydrodehalogenation methodology of o-haloanilides using EtOH as hydrogen source and solvent. The catalytic system could selectively dehalogenate 2-Br and 2-I, and features regioselective, efficient and functional group tolerance.

Chromium-catalyzed ligand-free amidation of esters with anilines

Amides are important structural motifs in pharmaceutical and agrochemical chemistry because of the intriguing biological active properties. We report here the amidation of commercially available esters with anilines that was promoted by low-cost and air-stable chromium(III) pre-catalyst combined with magnesium, providing access to amides. This reaction occurs without the use of external ligands in a simple operation. Mechanistic studies indicate that a reactive aminated Cr species responsible for the amidation can be considered, which may be formed by reaction of low-valent Cr with aniline followed by reduction with hydrogen evolution.