106392-26-1

Basic information

• Product Name: 4-(prop-2-yn-1-yl)-2,3,5,6-tetrafluorobenzyl alcohol
• Synonyms: 4-(prop-2-yn-1-yl)-2,3,5,6-tetrafluorobenzyl alcohol
• CAS NO: 106392-26-1
• Molecular Weight: 218.151
• Mol File: 106392-26-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(prop-2-yn-1-yl)-2,3,5,6-tetrafluorobenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(prop-2-yn-1-yl)-2,3,5,6-tetrafluorobenzyl alcohol(106392-26-1)
• EPA Substance Registry System: 4-(prop-2-yn-1-yl)-2,3,5,6-tetrafluorobenzyl alcohol(106392-26-1)

Safety Data

• Hazardous Substances Data: 106392-26-1(Hazardous Substances Data)

Upstream product

• 99705-46-1 4-(hydroxymethyl)-2,3,5,6-tetrafluorobenzyl bromide 
• 89343-06-6 tris-iso-propylsilyl acetylene 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 1164157-85-0 4-(2-propynyl)-2,3,5,6-tetrafluorobenzyl (1R)-trans-2,2,3-trimethylcyclopropanecarboxylate 
• 352664-73-4 4-propargyl-2,3,5,6-tetrafluorobenzyl-3-(1-propenyl)-2,2-dimethylcyclopropane carboxylate 
• 1160509-05-6 4-(2-propynyl)-2,3,5,6-tetrafluorobenzyl (1R)-trans-3-difluoromethyl-2,2-dimethylcyclopropanecarboxylate 

Relevant articles and documents

Synthesis method of fluorobenzyl ester insecticide key intermediate 4-propargyl-2, 3, 5, 6-tetrafluorobenzyl alcohol

A synthesis method of 4-propargyl-2, 3, 5, 6-tetrafluorobenzyl alcohol (I) comprises the following steps of: by using 4-hydroxymethyl-2, 3, 5, 6-tetrafluorobenzyl bromide (II) as a raw material, adding a chlorosilane reagent, an organic solvent and an alkaline substance, stirring and reacting at 0-30 DEG C for 2-10 hours, and carrying out post-treatment on the reaction solution to obtain a compound (III); dissolving the compound (III) and a compound (IV) in a reaction solvent; under the combined action of copper salt catalysis and 1, 10-phenanthroline ligand and an alkaline substance, stirringand reacting at 10-50 DEG C for 15-30 h; adding tetrabutylammonium fluoride into the reaction system, continuously stirring and reacting at 20-40 DEG C for 2-7 h, and carrying out post-treatment on the reaction liquid to obtain a target product (I). The method has the advantages of short steps, simple operation, mild reaction conditions, cheap and easily available raw materials, high yield, low cost, and easy realization of large-scale production.

Pyrimidine derivatives

A compound of formula: STR1 wherein R1 represents hydrogen or halogen, R2 represents an α-branched alkyl or a cycloalkyl group containing from 3 to 6 carbon atoms, Q represents hydroxy, halo, alkoxy of up to 6 carbon atoms or a group --OR where R represents the residue of an alcohol of formula ROH which forms an insecticidal ester when combined with crysanthemic acid, or 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid, or 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylic acid. The compounds are useful for combating insect and acarime pests.