106412-39-9Relevant academic research and scientific papers
Design, synthesis and SAR studies of GABA uptake inhibitors derived from 2-substituted pyrrolidine-2-yl-acetic acids
Steffan, Tobias,Renukappa-Gutke, Thejavathi,H?fner, Georg,Wanner, Klaus T.
, p. 1284 - 1306 (2015)
In this paper, we disclose the design and synthesis of a series of 2-substituted pyrrolidine-2-yl-acetic acid as core structures and the N-arylalkyl derivatives thereof as potential GABA transport inhibitors. The 2-position in the side chain of pyrrolidin
Catalytic Asymmetric Additions of Enol Silanes to In Situ Generated Cyclic, Aliphatic N-Acyliminium Ions
Aukland, Miles H.,Grossmann, Oleg,Lee, Sunggi,List, Benjamin,Maji, Rajat
supporting information, (2022/01/19)
Strong and confined imidodiphosphorimidate (IDPi) catalysts enable highly enantioselective substitutions of cyclic, aliphatic hemiaminal ethers with enol silanes. 2-Substituted pyrrolidines, piperidines, and azepanes are obtained with high enantioselectiv
A convenient allylsilane-N-acyliminium route toward 5-alkylindolizidines. Diastereoselective synthesis of (±)-indolizidine 167B
Peroche, Sandrine,Remuson, Roland,Gelas-Mialhe, Yvonne,Gramain, Jean-Claude
, p. 4617 - 4619 (2007/10/03)
A highly diastereoselective synthesis of 5-alkylindolizidines is described via an intermolecular addition of the allylsilyl functional group of homoallylic alcohols with an N-acyliminium ion derived from pyrrolidin-2-one.
REDUCTION OF N-ALKOXYCARBONYLLACTAMS WITH NaBH4/EtOH-H+: A FACILE SYNTHESIS OF α-ETHOXYURETHANES
Nagasaka, Tatsuo,Tamano, Hirohisa,Hamaguchi, Fumiko
, p. 1231 - 1232 (2007/10/02)
Reduction of N-alkoxycarbonyllactams with NaBH4/H+ in ethanol (Speckamp's condition) afforded α-ethoxyurethanes (Shono's compounds) in good yields.
