106429-45-2 Usage
Structure
Benzimidazole derivative containing a trifluoromethyl group
Usage
Building block in organic synthesis and medicinal chemistry
Pharmacological activities
Antifungal, antiviral, and antitumor properties
Trifluoromethyl group
Enhances lipophilicity and bioavailability
Value
Valuable scaffold for drug discovery and development
Versatility
Potential applications in various fields of research and industry
Check Digit Verification of cas no
The CAS Registry Mumber 106429-45-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,4,2 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 106429-45:
(8*1)+(7*0)+(6*6)+(5*4)+(4*2)+(3*9)+(2*4)+(1*5)=112
112 % 10 = 2
So 106429-45-2 is a valid CAS Registry Number.
106429-45-2Relevant academic research and scientific papers
Heterocyclic topoisomerase poisons
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, (2008/06/13)
The invention provides a topoisomerase poison of formula I: wherein R1-R8 have any of the meanings defined in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof.
