106429-52-1

Basic information

• Product Name: 1H-Benzimidazole-5-methanol,2-methyl-(9CI)
• Synonyms: 1H-Benzimidazole-5-methanol,2-methyl-(9CI);2-methyl-1H-Benzimidazole-6-methanol;(2-methyl-1H-benzo[d]imidazol-5-yl)methanol;(2-Methyl-1H-benzoimidazol-5-yl)-methanol;(2-methyl-1H-benzimidazol-5-yl)methanol
• CAS NO: 106429-52-1
• Molecular Formula: C9H10N2O
• Molecular Weight: 162.1885
• Product Categories: BENZIMIDAZOLE
• Mol File: 106429-52-1.mol

Chemical Properties

• Boiling Point: 442.4±20.0 °C(Predicted)
• Appearance: /
• Density: 1.295±0.06 g/cm3(Predicted)
• PKA: 11.97±0.10(Predicted)
• CAS DataBase Reference: 1H-Benzimidazole-5-methanol,2-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-5-methanol,2-methyl-(9CI)(106429-52-1)
• EPA Substance Registry System: 1H-Benzimidazole-5-methanol,2-methyl-(9CI)(106429-52-1)

Safety Data

• Hazardous Substances Data: 106429-52-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1H-Benzimidazole-5-methanol,2-methyl-(9CI) is used as a building block for the synthesis of various pharmaceuticals. Its unique structure and properties make it a promising candidate for the development of new drugs to treat a range of diseases.
Used in Agricultural Chemical Industry:
In the agricultural sector, 1H-Benzimidazole-5-methanol,2-methyl-(9CI) is utilized as a precursor in the synthesis of agricultural chemicals. Its chemical properties allow it to be incorporated into compounds that can be used for pest control and crop protection.
Used in Organic Synthesis:
1H-Benzimidazole-5-methanol,2-methyl-(9CI) is used as an intermediate in the synthesis of diverse organic compounds. Its versatility in chemical reactions makes it a valuable component in creating a wide array of organic molecules for various applications across different industries.

Upstream product

• 106429-51-0 methyl 2-methyl-1H-benzo[d]imidazole-6-carboxylate 
• 709-19-3 2-methyl-3H-benzo[d]imidazole-5-carboxylic acid 
• 717-37-3 ethyl 2-methyl-1H-benzimidazole-5-carboxylate 
• 106429-51-0 methyl 2-methylbenzimidazole-5-carboxylate hydrochloride 

Downstream Products

• 267875-44-5 5-(Aminomethyl)-2-methylbenzimidazole 

Relevant articles and documents

OGA INHIBITOR COMPOUNDS

The present invention relates to O-GlcNAc hydrolase (OGA) inhibitors. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which inhibition of OGA is beneficial, such as tauopathies, in particular Alzheimer's disease or progressive supranuclear palsy; and neurodegenerative diseases accompanied by a tau pathology, in particular amyotrophic lateral sclerosis or frontotemporal lobe dementia caused by C90RF72 mutations.

HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND USE THEREOF AS PROTEIN KINASE INHIBITORS

Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.

THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS

Invented is a method of inhibiting the activity/function of PI3 kinases using substituted thiazolones. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, ne

NOVEL CHEMICAL COMPOUNDS

This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with the imbalance or inappropriate activity of hYAK3 proteins.

Thrombin inhibitors

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: or a pharmaceutically acceptable salt thereof, wherein b is NY or O; c is CY2or N; d is CY3or N; e is CY4or N; f is CY5or N; g is CY6or N; Y4, Y5, and Y6are independently hydrogen, C1-4alkyl, or halogen; Y1and Y2are independently hydrogen, C1-4alkyl, C3-7cycloalkyl, halogen, NH2, OH or C1-4alkoxy, and Y3is hydrogen, C1-4alkyl, C3-7cycloalkyl, halogen, —CN, NH2, OH or C1-4alkoxy; A is and W, W1, R1, R3, R4, R5, X and Z are defined in the specification.

Thrombin inhibitors

Compounds of the invention are useful in inhibiting thrombin and treating blood coagulation and cardiovascular disorders and have the following structure: wherein R3 is hydrogen or halogen, and u is N or CH.

Novel β-lactam antibiotics

Antibacterially active and animal growth-promoting novel β-lactam compounds of the formula STR1 in which R1 represents the radical STR2 Y representing N or CR9, or Y--R7 representing >C=O or >C=N--R7, Z representing O, S, or NR10, and R2 represents hydrogen or a protective group.