106447-88-5Relevant articles and documents
SUBSTITUTED 6, 7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE 10A)
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Paragraph 0413; 0414, (2015/06/17)
The invention relates to compounds of the formula or a pharmaceutically acceptable salt thereof, wherein R′, R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.
6H-Isoxazolo[3,4-d]pyrazolo[3,4-b]pyridines, a process for their preparation and their use as medicaments
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, (2008/06/13)
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6H-isoxazolo[3,4-d]pyrazolo[3,4-b]pyridines, method for their preparation and use as anxiolytic agents
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, (2008/06/13)
There are disclosed compounds having the formula STR1 wherein R1 is hydrogen, loweralkyl, arylloweralkyl, aryl or heteroaryl; R2 is hydrogen or loweralkyl; R3 is loweralkyl, loweralkoxyloweralkyl, cycloalkyl, arylloweralky