1064678-66-5

Basic information

• Product Name: 3-Bromo-5-chloroisonicotinaldehyde
• Synonyms: 3-Bromo-5-chloro-4-formylpyridine;3-Bromo-5-chloroisonicotinaldehyde;3-Bromo-5-chloropyridine-4-carboxaldehyde;3-bromo-5-chloropyridine-4-carbaldehyde
• CAS NO: 1064678-66-5
• Molecular Formula: C₆H₃BrClNO
• Molecular Weight: 220.45112
• Mol File: 1064678-66-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 96-100°C
• Appearance: /
• CAS DataBase Reference: 3-Bromo-5-chloroisonicotinaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-5-chloroisonicotinaldehyde(1064678-66-5)
• EPA Substance Registry System: 3-Bromo-5-chloroisonicotinaldehyde(1064678-66-5)

Safety Data

• Hazard Codes: T,Xi
• Statements: 25-36/37/38
• Safety Statements: 26-39-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 1064678-66-5(Hazardous Substances Data)

Upstream product

• 73583-39-8 3-bromo-5-chloropyridine 
• 109-94-4 formic acid ethyl ester 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1308669-28-4 (S)-4-[5-chloro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-2-methoxy-benzonitrile 
• 1308669-25-1 (R)-4-[5-chloro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-2-methoxy-benzonitrile 
• 1308669-24-0 4-[5-chloro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-2-methoxy-benzonitrile 
• 1308669-22-8 (S)-2-chloro-4-[5-chloro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile 
• 1308669-21-7 (R)-2-chloro-4-[5-chloro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile 
• 1308669-20-6 2-chloro-4-[5-chloro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile 
• 1308669-19-3 2-chloro-4-(5-chloro-4-hydroxymethyl-pyridin-3-yl)-benzonitrile 

Relevant articles and documents

ARYL-PYRIDINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5 and n are defined herein. The invention also relates to a method for manufacturing compounds of the invention, and their therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS

The present invention is related to compound of the formula (I): or a pharmacologically acceptable salt, solvate, or hydrate thereof, wherein A is a 6-membered heteroaryl having from 1 to 3 heteroatoms, each independently selected from N or O and the other substituents are defined as in the claims.