106470-99-9

Basic information

• Product Name: 3(R^*)-hydroxy-4(S^*)-methyl-5(R^*)-isopropyltetrahydrofuran-2-one
• CAS NO: 106470-99-9
• Molecular Weight: 158.197
• Mol File: 106470-99-9.mol

Chemical Properties

• CAS DataBase Reference: 3(R^*)-hydroxy-4(S^*)-methyl-5(R^*)-isopropyltetrahydrofuran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3(R^*)-hydroxy-4(S^*)-methyl-5(R^*)-isopropyltetrahydrofuran-2-one(106470-99-9)
• EPA Substance Registry System: 3(R^*)-hydroxy-4(S^*)-methyl-5(R^*)-isopropyltetrahydrofuran-2-one(106470-99-9)

Safety Data

• Hazardous Substances Data: 106470-99-9(Hazardous Substances Data)

Upstream product

• 120313-28-2 (2S,3R,4S)-2,4-Dihydroxy-3,5-dimethyl-hexanoic acid diethylamide 
• 85710-97-0 (4R*,5R*)-4,5-dihydro-5-isopropyl-4-methyl-2(3H)-furanone 
• 120313-18-0 (R^*,S^*)-4-hydroxy-3,5-dimethyl-2-oxo-N,N-diethylhexanamide 
• 160741-81-1 (3S,4R,5R)-3-Hydroxy-5-isopropyl-4-methyl-dihydro-furan-2-one 

Relevant articles and documents

Kinetic Aldol Reactions of α-Keto Amides. Synthesis of the β-Methyl Glycosides of (-)-Cladinose and (+)-Mycarose

The first examples of nondehydrative, kinetic aldol condensations of 3-methyl and 3-phenoxy-2-oxo (tertiary) carboxamides are reported.Addition of hydride or methyl Grignard nucleophiles to the aldol products produced diol or monoprotected triol amides with high stereoselectivity in some cases.One of these compounds was elaborated to the methyl glycosides of (-)-cladinose and (+)-mycarose.