1064783-29-4

Basic information

• Product Name: 5-Chloro-3-fluoro-2-nitropyridine
• Synonyms: 5-Chloro-3-fluoro-2-nitropyridine
• CAS NO: 1064783-29-4
• Molecular Formula: C₅H₂ClFN₂O₂
• Molecular Weight: 176.5329832
• Mol File: 1064783-29-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 266.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.595±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -7.31±0.32(Predicted)
• CAS DataBase Reference: 5-Chloro-3-fluoro-2-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-3-fluoro-2-nitropyridine(1064783-29-4)
• EPA Substance Registry System: 5-Chloro-3-fluoro-2-nitropyridine(1064783-29-4)

Safety Data

• Hazardous Substances Data: 1064783-29-4(Hazardous Substances Data)

Usage

General Description

5-Chloro-3-flluoro-2-nitropyridine is a specialized chemical compound featuring in various scientific and industrial applications. It has a systematic name of 3-fluoro-5-chloro-2-nitropyridine and belongs to the class of organic compounds known as nitropyridines, which are compounds containing a pyridine ring which bears a nitro group. With the molecular formula C5H2ClFN2O2, it carries unique properties pertinent to its fluorine, chlorine, and nitro functional groups. It's used primarily in the field of material science and organic synthesis. Encompassing a slightly dense than water molecular weight of about 179.54 g/mol, this compound also exhibits a finely tuned balance of hydrophobicity and hydrophilicity due to its molecular structure, particularly useful in laboratory synthesis and industrial operations. More detailed properties such as solubility, stability and reactivity vary and should be availed under controlled conditions.

Upstream product

• 610278-88-1 3,5-dichloro-2-nitropyridine 
• 246847-98-3 5-chloro-3-fluoro-pyridine-2-amine 

Relevant articles and documents

COMPOUNDS AND THEIR METHODS OF USE

The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including Dravet syndrome or epilepsy are also provided herein.

TRICYCLIC COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS

The present invention provides compounds of Formula (A): (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent, and methods of using the compositions and combinations to treat conditions including cancers.

Certain Chemical Entities, Compositions, and Methods

Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of muscle weakness and/or cachexia, as part of a rehabilitation or conditioning exercise regimen, or in the treatment of fraility, post-polio syndrome, obesity, sarcopenia, wasting syndrome, muscle spasm, and other indications.