106492-20-0Relevant academic research and scientific papers
Reaction of Arylglyoxals with 2-Amino Heterocycles
Alcaide, Benito,Plumet, Joaquin,Sierra, Miguel A.,Vicent, Cristina
, p. 5763 - 5768 (2007/10/02)
The reaction of some arylglyoxals with a variety of 2-amino heterocycles, including pyridine, diazine, and azole derivatives, has been studied, with or without BF3*Et2O complex as catalyst.On the basis of the isolation of different intermediate carbinolamines and of some crossover cyclization experiments, a reasonable mechanism has been proposed for all these processes.In addition, some structural features of the resulting bicyclic imidazo derivatives having a potential hydroxyl group in position 3 are discussed.
