106500-89-4Relevant academic research and scientific papers
Folate Analogues as Inhibitors of Thymidylate Synthase
Brixner, Diana I.,Ueda, Takamori,Cheng, Yung-Chi,Hynes, John B.,Broom, Arthur D.
, p. 675 - 678 (2007/10/02)
Recent demonstrations that deazafolate analogues may act as potent inhibitors of thymidylate synthase (TS) provided a firm rationale for the synthesis of N10-propargyl derivatives of 8-deazafolate (3) and 8-deazaaminopterin (4).A complete assig
