1065074-18-1 Usage
General Description
4-(3-Chloro-4-methylphenyl)-1H-1,2,4-triazol-5(4H)-one, also known as CCTO, is a chemical compound with a molecular formula C9H7ClN4O. It is a triazolone herbicide and an active ingredient in various agricultural and horticultural products used to control a broad spectrum of weeds in crops. CCTO is effective in inhibiting the growth of weeds by disrupting the synthesis of certain amino acids and proteins essential for their survival. It is soluble in organic solvents and has low volatility, making it suitable for use as a herbicidal agent. However, it is important to handle and use CCTO with care due to its potential environmental and health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 1065074-18-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,5,0,7 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1065074-18:
(9*1)+(8*0)+(7*6)+(6*5)+(5*0)+(4*7)+(3*4)+(2*1)+(1*8)=131
131 % 10 = 1
So 1065074-18-1 is a valid CAS Registry Number.
1065074-18-1Relevant articles and documents
Design and synthesis of novel triazole antifungal derivatives by structure-based bioisosterism
Sheng, Chunquan,Che, Xiaoying,Wang, Wenya,Wang, Shengzheng,Cao, Yongbing,Miao, Zhenyuan,Yao, Jianzhong,Zhang, Wannian
experimental part, p. 5276 - 5282 (2011/12/03)
The incidence of life-threatening fungal infections is increasing dramatically. In an attempt to develop novel antifungal agents, our previously synthesized phenoxyalkylpiperazine triazole derivatives were used as lead structures for further optimization. By means of structure-based bioisosterism, triazolone was used as a new bioisostere of oxygen atom. This type of bioisosteric replacement can improve the water solubility without loss of hydrogen-bonding interaction with the target enzyme. A series of triazolone-containing triazoles were rationally designed and synthesized. As compared with fluconazole, several compounds showed higher antifungal activity with broader spectrum, suggesting their potential for further evaluations.
