1065074-49-8 Usage
General Description
Methyl 7-chloro-4-hydroxy-8-methylquinoline-2-carboxylate is a chemical compound used in the synthesis of pharmaceuticals and agrochemicals. It is a derivative of quinoline, a heterocyclic aromatic compound with a wide range of biological activities. This specific compound has a chlorine and hydroxyl group attached to the quinoline ring, as well as a methyl ester group at the 2-carboxylate position. These structural features may contribute to its potential biological and pharmacological properties, making it a valuable intermediate for the development of various drugs and pesticides. Further research and exploration of its chemical properties and applications may reveal its full potential in the fields of medicine and agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 1065074-49-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,5,0,7 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1065074-49:
(9*1)+(8*0)+(7*6)+(6*5)+(5*0)+(4*7)+(3*4)+(2*4)+(1*9)=138
138 % 10 = 8
So 1065074-49-8 is a valid CAS Registry Number.
1065074-49-8Relevant articles and documents
Synthesis of 2-(4-isopropylthiazol-2-yl)-7-methoxy-8-methylquinolin-4-ol; A quinoline building block for simeprevir synthesis
Rádl, Stanislav,Rezková, Hana,Obadalová, Iva,Srbek, Jan,B?ichá?, Ji?í,Pekárek, Tomá?
, p. 899 - 908 (2014/04/03)
Two synthetic approaches to the achiral quinoline fragment of simeprevir are described. Both approaches are based on the synthesis of methyl 4-hydroxy-7-methoxy-8-methylquinoline-2-carboxylate, protection of its 4-hydroxyl group, and construction of the thiazole ring from the ester group at the 2-position. The last step is acid deprotection of the 4-hydroxyl protecting group. Georg Thieme Verlag Stuttgart. New York.
