1065079-61-9

Basic information

• Product Name: C₁₉H₁₉N₃O₃
• Synonyms: C₁₉H₁₉N₃O₃
• CAS NO: 1065079-61-9
• Molecular Weight: 337.378
• Mol File: 1065079-61-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₉N₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₉N₃O₃(1065079-61-9)
• EPA Substance Registry System: C₁₉H₁₉N₃O₃(1065079-61-9)

Safety Data

• Hazardous Substances Data: 1065079-61-9(Hazardous Substances Data)

Upstream product

• 68062-88-4 N‐{2‐[5‐(benzyloxy)‐1H‐indol‐3‐yl]ethyl}acetamide 
• 2436-15-9 NSC 73391 
• 103-71-9 phenyl isocyanate 
• 1210-83-9 N-acetyl-5-hydroxytryptamine 

Relevant articles and documents

Biocatalytic C3-Indole Methylation—A Useful Tool for the Natural-Product-Inspired Stereoselective Synthesis of Pyrroloindoles

Enantioselective synthesis of bioactive compounds bearing a pyrroloindole framework is often laborious. In contrast, there are several S-adenosyl methionine (SAM)-dependent methyl transferases known for stereo- and regioselective methylation at the C3 position of various indoles, directly leading to the formation of the desired pyrroloindole moiety. Herein, the SAM-dependent methyl transferase PsmD from Streptomyces griseofuscus, a key enzyme in the biosynthesis of physostigmine, is characterized in detail. The biochemical properties of PsmD and its substrate scope were demonstrated. Preparative scale enzymatic methylation including SAM regeneration was achieved for three selected substrates after a design-of-experiment optimization.