1065102-79-5Relevant academic research and scientific papers
Highly Regioselective Iodination of Arenes via Iron(III)-Catalyzed Activation of N-Iodosuccinimide
Racys, Daugirdas T.,Warrilow, Catherine E.,Pimlott, Sally L.,Sutherland, Andrew
, p. 4782 - 4785 (2015)
An iron(III)-catalyzed method for the rapid and highly regioselective iodination of arenes has been developed. Use of the powerful Lewis acid, iron(III) triflimide, generated in situ from iron(III) chloride and a readily available triflimide-based ionic liquid allowed activation of N-iodosuccinimide (NIS) and efficient iodination under mild conditions of a wide range of substrates including biologically active compounds and molecular imaging agents.
Synthesis and properties of microenvironment-sensitive oligonucleotides containing a small fluorophore, 3-aminobenzonitrile or 3-aminobenzoic acid
Ozaki, Hiroaki,Kawai, Takeshi,Kuwahara, Masayasu
, p. 7177 - 7184 (2017/11/16)
Two C-nucleosides bearing small fluorescent groups as a base were synthesized by Heck-type coupling reaction and incorporated into DNA. They exhibited environment-sensitive fluorescence and opposite solvatochromic properties. The modified DNAs containing 3-aminobenzonitrile or 3-aminobenzoic acid retained the duplexes and their fluorescence reflected the microenvironment.
Palladium-catalyzed annulation reactions of methyl o-halobenzoates with azabicyclic alkenes: A general protocol for the construction of benzo[c]phenanthridine derivatives
Guo, Cui,Huang, Kanglun,Wang, Bo,Xie, Longguang,Xu, Xiaohua
, p. 17271 - 17280 (2013/09/24)
The annulation reaction of methyl o-halobenzoates with azabicyclic alkenes proceeds efficiently to give the corresponding benzo[c]phenanthridine derivatives in good to excellent yields using a developed base-free methodology based on our preliminary studies. Thirty-seven application examples validate the compatibility of the present strategy with different groups, particularly with the electron-deficient ones, that are difficult to access using other traditional methods. In addition, annulation reactions with non-symmetric azabicyclic alkenes are achieved in high regioselectivity.
