1065124-79-9

Upstream product

• 6097-26-3 p-methoxyphenacyl thiocyanate 
• 109-77-3 malononitrile 

Downstream Products

• 1396320-17-4 (E)-3-amino-2-[4-(4-methoxyphenyl)thiazol-2-yl]-3-piperidin-1-yl-acrylonitrile 
• 1396320-12-9 (E)-3-amino-2-[4-(4-methoxyphenyl)thiazol-2-yl]-3-morpholin-4-yl-acrylonitrile 
• 1396320-27-6 (E)-3-amino-3-(4-{(E)-1-amino-2-cyano-2-[4-(4-methoxyphenyl)thiazol-2-yl]vinyl}piperazin-1-yl)-2-[4-(4-methoxyphenyl)thiazol-2-yl]acrylonitrile 
• 1396320-22-1 (E)-3-amino-3-dimethylamino-2-[4-(4-methoxyphenyl)thiazol-2-yl]acrylonitrile 
• 1396320-24-3 (E)-3-amino-3-diethylamino-2-[4-(4-methoxyphenyl)thiazol-2-yl]acrylonitrile 

Relevant academic research and scientific papers

Dimedone-catalyzed addition of amines into cyano group: Facile synthesis of thiazol-2-yl substituted E-acrylonitriles

An efficient dimedone-catalyzed synthesis of highly functionalized thiazol-2-yl substituted E-acrylonitrile derivatives has been established through two-step reaction of α-thiocyanate ketones with malononitrile and amines. The α-thiocyanate ketones were s