1065166-57-5

Upstream product

• 1622220-02-3 2-(4-(difluoromethoxy)-3-methylphenyl)-1-(3-methylphenyl)-2-hydroxyethanone 
• 1622220-01-2 (4-(difluoromethoxy)-3-methylphenyl)(2-(3-methylphenyl)-1,3-dithian-2-yl)methanol 
• 62381-20-8 2-(3-methylphenyl)-1,3-dithiane 
• 620-23-5 m-tolyl aldehyde 
• 1062614-17-8 1-(4-(difluoromethoxy)-3-methylphenyl)-2-(3-methylphenyl)ethane-1,2-dione 
• 22661-87-6 1-methylguanidine hydrochloride 
• 1065169-16-5 1-(4-(difluoromethoxy)phenyl)-2-m-tolylethane-1,2-dione 

Relevant academic research and scientific papers

HYDANTOINS THAT MODULATE BACE-MEDIATED APP PROCESSING

In certain embodiments hydantoin compounds are provided herein that are effective to inhibit BACE activity against APP. Without being bound to a particular theory, it is believed the activity of the hydantoins identified herein appears to be associated wi

AMINO-5-[4-(DIFLUOROMETHOXY)PHENYL]-5-PHENYLIMIDAZOLONE COMPOUNDS FOR THE INHIBITION OF BETA-SECRETASE

The present invention provides compounds and methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.