1065183-64-3

Usage

Uses

1H-Indole-1-carboxylic acid, 6-fluoro-2,3-dihydro-, 1,1-dimethylethyl ester is used as a research chemical for [application reason] in the field of scientific experiments and research.
Used in Pharmaceutical Development:
1H-Indole-1-carboxylic acid, 6-fluoro-2,3-dihydro-, 1,1-dimethylethyl ester is used as a potential component in the development of pharmaceutical drugs for [application reason], such as targeting specific biological pathways or improving drug delivery systems.
Used in Chemical and Industrial Applications:
1H-Indole-1-carboxylic acid, 6-fluoro-2,3-dihydro-, 1,1-dimethylethyl ester is used as a chemical intermediate or reagent in various chemical and industrial processes for [application reason], including the synthesis of other compounds or materials with specific properties.

Upstream product

• 2343-23-9 6-fluoroindoline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1065183-63-2 (E)-(4-fluoro-2-nitrophenyl)ethanal semicarbazone 
• 446-10-6 2-nitro-4-fluorotoluene 
• 399-51-9 6-fluoro-1H-indole 

Downstream Products

• 1065179-16-9 3-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-6-fluoro-5-phenyl-1H-indole-7-carboxamide 

Relevant academic research and scientific papers

4,5,6,7-TETRAHYDRO-1 H-PYRAZOLO[4,3-C]PYRIDIN-3-AMINE COMPOUNDS AS CBP AND/OR EP300 INHIBITORS

The present invention relates to compounds of formula (I) or formula (II): and to salts thereof, wherein R1-R4 of formula (I) and R1-R3 of formula (II) have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) of formula (II) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.

INDOLE CARBOXAMIDES AS IKK2 INHIBITORS

The invention is directed to novel indole carboxamide compounds. Specifically, the invention is directed to compounds according to formula (I): wherein R1, R2, R3, R4, and m are as defined herein. The compounds of the invention are inhibitors of IKK2 and can be useful in the treatment of disorders associated with inappropriate IKK2 (also known as IKKβ) activity, such as rheumatoid arthritis, asthma, rhinitis, and COPD (chronic obstructive pulmonary disease). Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting IKK2 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

PURINE DERIVATIVES AS KINASE INHIBITORS

The present invention provides kinase inhibitors of Formula I.