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3-[(2R,3S,5R)-5-(6-chloro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl]-1-phenylpropan-1-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1065269-45-5

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1065269-45-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1065269-45-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,5,2,6 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1065269-45:
(9*1)+(8*0)+(7*6)+(6*5)+(5*2)+(4*6)+(3*9)+(2*4)+(1*5)=155
155 % 10 = 5
So 1065269-45-5 is a valid CAS Registry Number.

1065269-45-5Downstream Products

1065269-45-5Relevant academic research and scientific papers

Synthesis and evaluation of 5′-modified 2′-deoxyadenosine analogues as anti-hepatitis C virus agents

Ikejiri, Masahiro,Ohshima, Takayuki,Fukushima, Akemi,Shimotohno, Kunitada,Maruyama, Tokumi

supporting information; experimental part, p. 4638 - 4641 (2009/04/08)

In order to study the effect of 5′-modification of 2′-deoxynucleoside on its anti-HCV activity, several analogues were synthesized and evaluated. Among the analogues, a 5′-deoxy-5′-phenacylated analogue exhibited a good anti-HCV activity with an EC50 of 15.1 μM. This compound is expected to operate via a type of mechanism that does not involve a generally known 5′-O-triphosphorylation process.

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