Cas 1065269-49-9,(E)-3-[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-(tert-butyldimethylsilyloxy)tetrahydrofuran-2-yl]-1-phenylprop-2-en-1-one

1065269-49-9

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Product Name: (E)-3-[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-(tert-butyldimethylsilyloxy)tetrahydrofuran-2-yl]-1-phenylprop-2-en-1-one
Synonyms: (E)-3-[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-(tert-butyldimethylsilyloxy)tetrahydrofuran-2-yl]-1-phenylprop-2-en-1-one
CAS NO:1065269-49-9
Molecular Formula:
Molecular Weight: 465.627
EINECS: N/A
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Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (E)-3-[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-(tert-butyldimethylsilyloxy)tetrahydrofuran-2-yl]-1-phenylprop-2-en-1-one(CAS DataBase Reference)
NIST Chemistry Reference: (E)-3-[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-(tert-butyldimethylsilyloxy)tetrahydrofuran-2-yl]-1-phenylprop-2-en-1-one(1065269-49-9)
EPA Substance Registry System: (E)-3-[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-(tert-butyldimethylsilyloxy)tetrahydrofuran-2-yl]-1-phenylprop-2-en-1-one(1065269-49-9)

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Safety Statements: N/A
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RTECS:
HazardClass: N/A
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Hazardous Substances Data: 1065269-49-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1065269-49-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,5,2,6 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1065269-49:
(9*1)+(8*0)+(7*6)+(6*5)+(5*2)+(4*6)+(3*9)+(2*4)+(1*9)=159
159 % 10 = 9
So 1065269-49-9 is a valid CAS Registry Number.

1065269-49-9Upstream product

1065269-49-9Downstream Products

1065269-51-3 3-[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-(tert-butyldimethylsilyloxy)tetrahydrofuran-2-yl]-1-phenylpropan-1-one

1065269-49-9Relevant academic research and scientific papers

Synthesis and evaluation of 5′-modified 2′-deoxyadenosine analogues as anti-hepatitis C virus agents

Ikejiri, Masahiro,Ohshima, Takayuki,Fukushima, Akemi,Shimotohno, Kunitada,Maruyama, Tokumi

, p. 4638 - 4641 (2008)

In order to study the effect of 5′-modification of 2′-deoxynucleoside on its anti-HCV activity, several analogues were synthesized and evaluated. Among the analogues, a 5′-deoxy-5′-phenacylated analogue exhibited a good anti-HCV activity with an EC50 of 15.1 μM. This compound is expected to operate via a type of mechanism that does not involve a generally known 5′-O-triphosphorylation process.

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