106535-19-7

Basic information

• Product Name: METHYL-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPIONATE
• Synonyms: METHYL-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPIONATE;methyl 3-(1,2,4-triazol-1-yl)propanoate
• CAS NO: 106535-19-7
• Molecular Formula: C6H9N3O2
• Molecular Weight: 155.15
• Mol File: 106535-19-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 290.1 °C at 760 mmHg
• Flash Point: 129.2 °C
• Appearance: /
• Density: 1.25 g/cm³
• Vapor Pressure: 0.00212mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: METHYL-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPIONATE(106535-19-7)
• EPA Substance Registry System: METHYL-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPIONATE(106535-19-7)

Safety Data

• Hazardous Substances Data: 106535-19-7(Hazardous Substances Data)

Usage

General Description

Methyl-3-(1H-1,2,4-triazole-1-yl)-propionate is a chemical compound with the molecular formula C7H10N4O2. It belongs to the class of propionate esters and contains a triazole ring in its structure. METHYL-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPIONATE is commonly used in organic synthesis and medicinal chemistry as a building block for the production of various pharmaceuticals, agrochemicals, and other fine chemicals. It has potential applications in the development of antifungal agents, herbicides, and insecticides. Additionally, it may also be used as a flavoring agent in the food industry. Overall, methyl-3-(1H-1,2,4-triazole-1-yl)-propionate is a versatile chemical with diverse applications in different industries.

InChI:InChI=1/C6H9N3O2/c1-11-6(10)2-3-9-5-7-4-8-9/h4-5H,2-3H2,1H3

Upstream product

• 288-88-0 1,2,4-Triazole 
• 292638-85-8 acrylic acid methyl ester 

Relevant articles and documents

Mild and efficient procedure for michael addition of n-heterocycles to,-unsaturated compounds using anhydrous K3PO4 as catalyst

Imidazole, 1,2,4-triazole, indole, and benzotriazole undergo conjugate additions with,α,β-unsaturated carbonyl compounds in the presence of anhydrous potassium phosphate at ambient temperature to afford the corresponding Michael adducts in excellent yields.

Solvent- and Catalyst-Free Aza-Michael Addition of Imidazoles and Related Heterocycles

This work demonstrates the scope and limitations of the aza-Michael addition of imidazoles and related heterocycles with electron deficient olefins under solvent- and catalyst-free conditions. The reaction proceeds at 80 °C within hours towards completion as long as the azole derivative is sufficiently soluble in the Michael acceptor, which has been used in small excess. Workup only comprises evaporation of surplus Michael-acceptor, and no additional solvents are necessary for purifying the products.

Poly(N-vinylimidazole) as an efficient and recyclable catalyst of the aza-Michael reaction in water

Poly(N-vinylimidazole) effectively catalyzed Michael addition of 1H-1,2,4-triazole, 3,5-dimethyl-1H-1,2,4-triazole, uracil, oxazolidin-2-one, and succinimide to but-3-en-2-one, cyclohex-2-en-1-one, methyl acrylate, and methyl vinyl sulfone in water at roo