106538-16-3Relevant academic research and scientific papers
A New Synthesis of Novel 1-Aryl-3-heteroaryl-1H-pyrazoloquinoxalines via a Key Intermediate
Kurasawa, Yoshihisa,Muramatsu, Muneto,Yamazaki, Kaoru,Tajima, Setsuko,Okamoto, Yoshihisa,Takada, Atsushi
, p. 633 - 635 (2007/10/02)
The chlorination of the α-hydrazonoester 4 with phosphoryl chloride/pyridine gave 3--2-chloroquinoxaline 5, whose cyclization with 1,8-diazabicyclo-7-undecene afforded 3-methoxycarbonyl-1-(o-chlorop
A Convenient Synthesis and Antifungal Activity of 1-Aryl-1H- and 1-Aryl-3-heteroaryl-1H-pyrazoloquinoxalines
Kurasawa, Yoshihisa,Muramatsu, Muneto,Yamazaki, Kaoru,Tajima, Setsuko,Okamoto, Yoshihisa,Takada, Atsushi
, p. 1379 - 1382 (2007/10/02)
Novel 1-aryl-1H- and 1-aryl-3-heteroaryl-1H-pyrazoloquinoxalines (flavazoles) 9a-c, 12, 13 were synthesized from 3-methyl-2-oxo-1,2-dihydroquinoxaline 5 and the 3-triazolylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxaline 6, respectively, via a facile hydrazone synthesis using aryl diazonium salts.Some of the above flavazoles and their related compounds exhibited the antifungal activity in some extent.The above results are described.
A New Method for the Synthesis of Novel 1-Aryl-3-heteroaryl-1H-pyrazoloquinoxalines
Kurasawa, Yoshihisa,Muramatsu, Muneto,Yamazaki, Kaoru,Tajima, Setsuko,Okamoto, Yoshihisa,Takada, Atsushi
, p. 959 - 960 (2007/10/02)
The reaction of 3-(2,3-dihydro-4-methyl-3-thioxo-4H-1,2,4-triazol-5-ylmethylene)-2-oxo-1,2,3,4-tetrahydroquinoxaline 4 with o-chlorobenzenediazonium chloride gave 3--2-
A Facile Synthesis of 1-Aryl-3-heteroaryl-1H-pyrazoloquinoxalines and Related Compounds with Antifungal Activity
Kurasawa, Yoshihisa,Muramatsu, Muneto,Yamazaki, Kaoru,Tajima, Setsuko,Okamoto, Yoshihisa,Takada, Atsushi
, p. 1391 - 1394 (2007/10/02)
The novel 1H-pyrazoloquinoxalines (flavazoles) 9-15 were synthesized from 3-methoxycarbonylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxaline 6 via a convenient hydrazone synthesis, and these flavazoles were clarified to have the antifungal activity.
