106540-89-0

Upstream product

• 108-98-5 thiophenol 
• 106540-88-9 Acetic acid (2R,3S)-3-acetoxy-5-oxo-1-(4-trimethylsilanyl-but-3-ynyl)-pyrrolidin-2-yl ester 
• 106540-87-8 (4S,5S)-4,5-diacetoxy-1-(4-trimethylsilyl-3-butynyl)-2-pyrrolidinone 
• 106540-84-5 (3S)-3-acetoxy-1-(4-trimethylsilyl-3-butynyl)-2,5-pyrrolidindione 
• 85319-59-1 (3S)-acetoxy-2,5-pyrrolidinedione 
• 106540-85-6 (4S,5S)-4-acetoxy-5-hydroxy-1-(4-trimethylsilyl-3-butynyl)-2-pyrrolidinone 
• 106540-86-7 Acetic acid (2R,3S)-2-hydroxy-5-oxo-1-(4-trimethylsilanyl-but-3-ynyl)-pyrrolidin-3-yl ester 

Relevant academic research and scientific papers

α-ACYLAMINORADICAL ANNELATION IN THE DIASTEREOSELECTIVE SYNTHESIS OF 1- AND 5-SUBSTITUTED TETRAHYDROPYRROLOOXAZOLE AND 1-SUBSTITUTED PYRROLIZIDINE DERIVATIVES

Diastereoselective synthesis of 1,8-trans-1-substituted and 5,8-trans-5-substituted tetrahydropyrrolooxazoles was achieved by an application of α-acylaminoradical cyclization at a silylated triple bond.The method was applied to an enantioselective

FREE RADICAL CYCLIZATIONS IN ALKALOID SYNTHESIS: (+)-HELIOTRIDINE AND (+)-HASTANECINE

Treatment of phenylthiolactams 5a-5f with tri-n-butyltin hydride and AIBN affords mixtures of reduction and cyclization products.Cyclization products partition between indolizidinones and pyrrolizidinones depending on the terminal alkyne substituent.When