1065488-49-4Relevant academic research and scientific papers
Iodine-mediated electrophilic cyclization of 2-alkynylbenzaldoximes leading to the formation of iodoisoquinoline N-oxides
Huo, Zhibao,Tomeba, Hisamitsu,Yamamoto, Yoshinori
, p. 5531 - 5533 (2008)
Reaction of 2-alkynylbenzaldoximes 1 with 5 equiv of iodine in EtOH at room temperature gives the corresponding iodoisoquinoline N-oxides 2 in good to excellent yields. The cyclization proceeds very smoothly and quickly without any additives such as bases
