1065559-56-9 Usage
General Description
SMND-309 is a chemical compound known for its potential therapeutic applications as a selective estrogen receptor degrader (SERD). It has been studied for its ability to specifically target and degrade the estrogen receptor, which is a protein commonly involved in the development and progression of certain types of breast cancer. SMND-309 is being researched as a potential treatment for hormone receptor-positive breast cancer, which accounts for a significant portion of breast cancer cases. Studies have shown promising results in preclinical models, and further research is ongoing to investigate its safety and efficacy in human clinical trials. If successful, SMND-309 could offer a new and effective option for the treatment of estrogen receptor-positive breast cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1065559-56-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,5,5,5 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1065559-56:
(9*1)+(8*0)+(7*6)+(6*5)+(5*5)+(4*5)+(3*9)+(2*5)+(1*6)=169
169 % 10 = 9
So 1065559-56-9 is a valid CAS Registry Number.
1065559-56-9Relevant articles and documents
Synthesis of SMND-309, a derivate of salvianolic acid B
Wu, Kong,Song, Chan,Cui, Dong-Mei,Zhang, Chen
, p. 1387 - 1391 (2017)
(E)-2-(6-((E)-2-carboxyvinyl)-2,3-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl) acrylic acid, designated SMND-309, was synthesized starting from 2-hydroxy-3-methoxybenzaldehyde in 12 steps and with an overall yield of 44%. The synthetic key features were the c
