1065628-56-9Relevant academic research and scientific papers
Synthesis and Antimalarial Activity of Dihydroperoxides and Tetraoxanes Conjugated with Bis(benzyl)acetone Derivatives
Franco, Lucas Lopardi,de Almeida, Mauro Vieira,e Silva, Luiz Francisco Rocha,Vieira, Pedro Paulo Ribeiro,Pohlit, Adrian Martin,Valle, Marcelo Siqueira
experimental part, p. 790 - 797 (2012/06/18)
Dihydroperoxides and tetraoxanes derived from symmetrically substituted bis(arylmethyl)acetones were synthesized in modest to good yields using several methods. Three of these compounds exhibit an important in vitro antimalarial activity (1.0μm≤IC50≤5.0μm) against blood forms of the human malaria parasite Plasmodium falciparum.
Mild and efficient Re(VII)-catalyzed synthesis of 1,1-dihydroperoxides
Ghorai, Prasanta,Dussault, Patrick H.
supporting information; body text, p. 4577 - 4579 (2009/05/11)
(Chemical Equation Presented) Re2O7 in CH 3CN is a remarkably efficient and mild catalyst for the peroxyacetalization of ketones, aldehydes, or acetals by H2O 2 to generate 1,1-dihydroperoxides. Me3SiOReO3 and methyl rhenium trioxide (MTO) are also effective catalysts under these reaction conditions.
