1065628-85-4

Upstream product

• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1094165-47-5 C₁₇H₁₉ClO₄ 
• 1094165-46-4 3-(4-chloro-phenyl)-9-tert-butyl-1,2,4,5-tetraoxaspiro[5.5]undecane 
• 1394206-97-3 3-(4-chlorophenyl)-9-methyl-1,2,4,5-tetraoxaspiro[5.5]undecane 
• 1018987-91-1 3-(4-chlorophenyl)-1,2,4,5-tetraoxaspiro[5.5]undecane 
• 16204-39-0 3,6-bis-(4-chloro-phenyl)-[1,2,4,5]tetroxane 

Relevant academic research and scientific papers

Sulfamic acid: as a green and reusable homogeneous catalyst for peroxidation of ketones and aldehydes using aqueous 30 % H2O2

Abstract Sulfamic acid has been used as an active, low-cost and reusable solid catalyst for conversion of ketones and aldehydes to corresponding gem-dihydroperoxides using 30 % aqueous hydrogen peroxide at room temperature. The reactions proceed with high rates and excellent yields.

Synthesis of Primary gem-Dihydroperoxides and Their Peroxycarbenium [3 + 2] Cycloaddition Reactions with Alkenes

It is long known that dihydroperoxidation of aliphatic aldehydes is extremely difficult and normally stops halfway at the hydroxyhydroperoxide stage. This strange phenomenon now has been explored, and a highly effective protocol for conversion of aliphatic aldehydes into gem-dihydroperoxides has been developed. Silyl protection of primary gem-dihydroperoxides, which is also a challenge due to unexpected based-induced decomposition, was achieved using 2,6-lutidine as the base. The silyl-protected gem-dihydroperoxides were then examined in a peroxycarbenium [3 + 2] cycloaddition reaction with alkenes for the first time. Aromatic substrates normally reacted smoothly, affording the expected 1,2-dioxolanes smoothly. Aliphatic aldehydes generally failed to yield 1,2-dioxolane. In all cases, unexpected formation of either a chlorohydrin or a 1,2-dichloride (with Cl atoms derived from TiCl4) depending on the alkene employed was observed, which displays some so far unknown facets of the cycloaddition and helped to gain many mechanistic insights.

Heteropoly acid/NaY zeolite as a reusable solid catalyst for highly efficient synthesis of gem-dihydroperoxides and 1,2,4,5-Tetraoxanes

Gem-Dihydroperoxides and 1,2,4,5-Tetraoxanes were synthesised from aldehydes and ketones catalysed by heteropoly acid/NaY zeolite (HPA/NaY) as a new, effective and reusable solid catalyst using 30% aqueous hydrogen peroxide at room temperature. The reactions proceeded with high rates and excellent yields.

Synthesis of gem-dihydroperoxides from ketones and aldehydes using silica sulfuric acid as heterogeneous reusable catalyst

Silica sulfuric acid (SSA) was found to efficiently catalyze the conversion of aldehydes and ketones directly into the corresponding gem-dihydroperoxides (DHPs) on treatment with aqueous 30% H2O2 at room temperature. Mild reaction conditions, good to excellent yields, short reaction times, low environmental impact, and recyclability of the catalyst are the main advantages of this synthetic method.

Triflic acid-functionalized silica-coated magnetic nanoparticles as a magnetically separable catalyst for synthesis of gem-dihydroperoxides

Triflic acid-functionalized silica-coated magnetic nanoparticles [γ-Fe2O3@SiO2-TfOH] were readily prepared and identified as an effictive catalyst for the transformation of aldehydes or ketones into their corresponding gem-dihydroperoxides with 30% aqueous hydrogen peroxide. The catalyst was easily separated by magnetic decantation and the recovered catalyst was reused for seven cycles without significant loss of catalytic activity. Copyright

Zinc chloride anhydrous as new and effective catalyst for conversion of ketones and aldehydes to corresponding gem-dihydroperoxides

Zinc chloride anhydrous has been used as an efficient and new catalyst for conversion of ketones and aldehydes to corresponding gem-dihydroperoxides by aqueous hydrogen peroxide (30%) in room temperature with excellent yields and notable reaction times.

A facile and efficient Bi(III) catalyzed synthesis of 1,1-dihydroperoxides and 1,2,4,5-tetraoxanes

Bismuth triflate is a remarkably efficient and mild catalyst for the synthesis of both 1,1-dihydroperoxides and 1,2,4,5-tetraoxanes. The successful application of this methodology for the synthesis of both symmetrical and unsymmetrical tetraoxanes is demonstrated.

AlCl3.6H2O as a catalyst for simple and efficient synthesis of gem-dihydroperoxides from ketones and aldehydes using aqueous H2O2

AlCl3.6H2O was explored as an efficient catalyst for the synthesis of gem-dihydroperoxides (DHPs) from ketones and aldehydes. The reactions took place within a short period of time using (30%) aqueous H 2O2 as a "green" oxidant in acetonitrile under neutral conditions at room temperature to afford the products in high yields.

Mild and efficient strontium chloride hexahydrate-catalyzed conversion of ketones and aldehydes into corresponding gem-dihydroperoxides by aqueous H 2O2

SrCl2·6H2O has been shown to act as an efficient catalyst for the conversion of aldehydes or ketones into the corresponding gem-dihydroperoxides (DHPs) by treatment with aqueous H 2O2 (30%) in acetonitrile. The reactions proceed under mild and neutral conditions at room temperature to afford good to excellent yields of product.

Stannous chloride dihydrate: A novel and efficient catalyst for the synthesis of gem-dihydroperoxides from ketones and aldehydes

Ketones and aldehydes undergo facile hydroperoxidation on treatment with aqueous hydrogen peroxide (30%) in the presence of 10 mol% stannous chloride dihydrate in acetonitrile under very mild conditions to afford the corresponding gem-dihydroperoxides in satisfactory yields. Georg Thieme Verlag Stuttgart.