106565-71-3 Usage
Uses
Used in Pharmaceutical Industry:
(3S,5R,8aS)-(+)-Hexahydro-3-phenyl-5H-oxazolo[3,2-a]pyridine-5-carbonitrile is used as a starting material for the preparation of spirocyclic aminochroman derivatives. These derivatives have the potential to act as 5-HT1A agonists, which are important in the treatment of various neurological and psychiatric disorders.
Used in Anticancer Applications:
In the field of cancer research, (3S,5R,8aS)-(+)-Hexahydro-3-phenyl-5H-oxazolo[3,2-a]pyridine-5-carbonitrile is utilized in the asymmetric synthesis of aza-analogs of podophyllotoxin. Podophyllotoxin is a potent antitumor agent, and its aza-analogs are being investigated for their potential to improve the efficacy and reduce the side effects of cancer treatments.
These applications highlight the versatility of (3S,5R,8aS)-(+)-Hexahydro-3-phenyl-5H-oxazolo[3,2-a]pyridine-5-carbonitrile in both the pharmaceutical and anticancer industries, showcasing its potential as a valuable compound for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 106565-71-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,5,6 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 106565-71:
(8*1)+(7*0)+(6*6)+(5*5)+(4*6)+(3*5)+(2*7)+(1*1)=123
123 % 10 = 3
So 106565-71-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H16N2O/c15-9-12-7-4-8-14-16(12)13(10-17-14)11-5-2-1-3-6-11/h1-3,5-6,12-14H,4,7-8,10H2/t12-,13-,14+/m1/s1
106565-71-3Relevant academic research and scientific papers
Guz, Nathan R.,Pfeiffer, Matt,Dickman, Dan
, p. 1476 - 1478 (2010)
An improved preparation at kilolaboratory scale of the CNRS chiral auxiliary is presented.
