106577-69-9Relevant academic research and scientific papers
Studies on Heterocyclic Analogues of Azulene. Part 15. Synthesis of Cycloheptimidazole &β-Ribonucleosides and Cycloheptapyrrole &α- and &β-Arabinonucleosides
Nishiwaki, Tarozaemon,Fukui, Toshimi
, p. 2625 - 2644 (2007/10/02)
1-(β-D-Ribofuranosyl)cycloheptimidazole-2(1H)-thione (4a) and its 2-oxo analogue (4b) and 1-(β-D-arabinofuranosyl)cycloheptapyrrol-2(1H)-one (13) and its α-isomer (19) were prepared.The first two and the last were obtained by the reaction of the corresponding silylated base with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose or 1-O-acetyl-2,3,5-tri-O-benzoyl-D-arabinofuranose in the presence of a Lewis catalyst, whereas the third was synthesized by the oxidation followed by reduction of 1-(3',5'-di-O-benzoyl-β-D-ribofuranosyl)cycloheptapyrrol-2(1H)-one.Synthesis of the last compound was accompanied by the formation of 3-(α- and β-D-arabinofuranosyl)cycloheptapyrrol-2(1H)-ones (20-21).
