106595-71-5Relevant academic research and scientific papers
Synthesis and structure-activity relationships of 2-(substituted phenyl)-3-[3-(N,N-dimethylamino)propyl]-1,3-thiazolidin-4-ones acting as H1-histamine antagonists
Diurno, M. Vittoria,Mazzoni, Orazio,Correale, Gaetano,Gomez Monterrey, Isabel,Calignano, Antonio,La Rana, Giovanna,Bolognese, Adele
, p. 579 - 583 (1999)
2-(Substituted-phenyl)-3-[3-(N,N-dimethylamino)propyl]-1,3-thiazolidin-4-ones (1-15) showed dependence of the potency of the H1-histamine antagonism on the m- and p-substituents suggesting that the aromatic moiety binds the receptor by a strong
