106652-61-3Relevant academic research and scientific papers
PCP receptor and dopamine uptake sites are discriminated by chiral TCP and BTCP derivatives of opposite configuration
Coderc, E.,Cerruti, P.,Vignon, J.,Rouayrenc, J. F.,Kamenka, J. M.
, p. 463 - 470 (1995)
3-Methylpiperidine derivatives of 1-piperidine (TCP) and 1-thiophenyl)cyclohexyl>piperidine (BTCP) were obtained in their racemic and homochiral forms.They have been tested for their affinity for the K receptor label
Substituted cyclic amines and pharmaceutical composition containing them
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, (2008/06/13)
The invention relates to substituted arylamines and heteroarylamines, their preparation process and the pharmaceutical composition containing them. Said substituted amine is in accordance with the formula: STR1 in which R1 and R2 are optionally substituted alkyl radicals or form with N an optionally substituted piperazine or piperidine cycle, R3 and R4 represent a hydrogen atom or an organic radical, Y represents CR6 or N and R5 is an optionally substituted benzothiophenyl, benzofuranyl or naphthyl radical. These amines can be used in pharmaceutical compositions for the treatment of nervous depression or for stimulating vigilance.
