106658-35-9Relevant academic research and scientific papers
INDAZOLINONE COMPOSITIONS USEFUL AS KINASE INHIBITORS
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Page 188, (2008/06/13)
The present invention provides compounds of formula (I): These compounds, and pharmaceutically acceptable compositions thereof, are useful generally as kinase inhibitors, particularly as inhibitors of PRAK, GSK3, ERK2, CDK2, MK2, SRC, SYK, and Aurora-2. Accordingly, compounds and compositions of the invention are useful for treating or lessening the severity of a variety of disorders, including, but not limited to, heart disease, diabetes, Alzheimer's disease, immunodeficiency disorders, inflammatory diseases, allergic diseases, autoimmune diseases, destructive bone disorders such as osteoporosis, proliferative disorders, infectious diseases and viral diseases.
REACTIONS OF ARYLPROPIOLAMIDES WITH ARYLACETAMIDES
Al-Arab, Mohammad M.
, p. 2910 - 2913 (2007/10/02)
The reaction of 3-phenylpropiolamide with phenylacetamide yielded 2-benzyl-4-phenyl-6-pyrimidone, whilst that of o-chlorophenylpropiolamide with phenylacetamide or p-chlorophenylacetamide yielded the 4-(o-chlorophenyl)pyrimidine-2,6-dione.The reaction products were identified from their spectral analysis.
