106660-41-7Relevant academic research and scientific papers
A Convenient Synthesis and Antifungal Activity of 1-Aryl-1H- and 1-Aryl-3-heteroaryl-1H-pyrazoloquinoxalines
Kurasawa, Yoshihisa,Muramatsu, Muneto,Yamazaki, Kaoru,Tajima, Setsuko,Okamoto, Yoshihisa,Takada, Atsushi
, p. 1379 - 1382 (2007/10/02)
Novel 1-aryl-1H- and 1-aryl-3-heteroaryl-1H-pyrazoloquinoxalines (flavazoles) 9a-c, 12, 13 were synthesized from 3-methyl-2-oxo-1,2-dihydroquinoxaline 5 and the 3-triazolylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxaline 6, respectively, via a facile hydrazone synthesis using aryl diazonium salts.Some of the above flavazoles and their related compounds exhibited the antifungal activity in some extent.The above results are described.
A Facile Synthesis of Novel 1-Aryl-1H-pyrazoloquinoxalines
Kurasawa, Yoshihisa,Yamazaki, Kaoru,Tajima, Setsuko,Okamoto, Yoshihisa,Takada, Atsushi
, p. 281 - 282 (2007/10/02)
The reactions of 3-methyl-2-oxo-1,2-dihydroquinoxaline 3 with chlorophenyl diazonium salts afforded the hydrazones 4a-c, whose chlorinations with phosphoryl chloride gave the dichlorides 5a-c.Refluxing of the dichlorides 5a-c and base in N,N-dimethylformamide provided the 1-aryl-1H-pyrazoloquinoxalines 6a-c.
