106666-45-9Relevant articles and documents
Synthesis and evaluation of thiophene based small molecules as potent inhibitors of Mycobacterium tuberculosis
Asthana, Shailendra,Kumar, Arun,Kumar, Varun,Mahajan, Dinesh,Meena, Chhuttan L.,Shaliwal, Ravi P.,Singh, Padam,Singh, Ramandeep,Tiwari, Anoop Kumar
, (2020/09/17)
Herein, we report the synthesis and anti-tubercular studies of novel molecules based on thiophene scaffold. We identified two novel small molecules 4a and 4b, which demonstrated 2-fold higher in vitro activity (MIC99: 0.195 μM) compared to firs