106711-70-0

Basic information

• Product Name: C₅₈H₉₄O₁₇Si₃
• Synonyms: C₅₈H₉₄O₁₇Si₃
• CAS NO: 106711-70-0
• Molecular Weight: 1147.63
• Mol File: 106711-70-0.mol

Chemical Properties

• CAS DataBase Reference: C₅₈H₉₄O₁₇Si₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₈H₉₄O₁₇Si₃(106711-70-0)
• EPA Substance Registry System: C₅₈H₉₄O₁₇Si₃(106711-70-0)

Safety Data

• Hazardous Substances Data: 106711-70-0(Hazardous Substances Data)

Upstream product

• 109922-70-5 Acetic acid (2S,3R,4S,5R,6R)-2-((3R,4R,5R,6R)-4-acetoxy-2-hydroxy-6-methyl-5-triethylsilanyloxy-tetrahydro-pyran-3-yloxy)-6-methyl-3,5-bis-triethylsilanyloxy-tetrahydro-pyran-4-yl ester 
• 114828-03-4 C₂₄H₂₈O₇ 
• 106711-69-7 C₄₉H₈₈O₁₆Si₃ 
• 102-92-1 Cinnamoyl chloride 
• 18439-45-7 3-O-Benzyl-6-desoxy-1,2-O-isopropyliden-α-D-gluco-hexofuranose 
• 994-30-9 triethylsilyl chloride 
• 106711-50-6 3-O-Benzyl-6-deoxy-D-glucose 
• 106711-53-9 C₁₈H₂₄O₅ 
• 106711-52-8 Acetic acid (2R,3R,4S,5R,6R)-5-acetoxy-4-benzyloxy-2-bromo-6-methyl-tetrahydro-pyran-3-yl ester 
• 106711-54-0 C₂₀H₂₆O₆ 
• 106711-58-4 Acetic acid (2R,3R,4S,5R,6R)-6-allyloxy-4-benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-diacetoxy-4-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-methyl-tetrahydro-pyran-3-yl ester 
• 106711-57-3 Acetic acid (2R,3R,4S,5R,6S)-6-allyloxy-4-benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-diacetoxy-4-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-methyl-tetrahydro-pyran-3-yl ester 
• 134333-38-3 Acetic acid (2S,3R,4S,5R,6R)-2-((2S,3R,4R,5R,6R)-4-acetoxy-2-formyloxy-6-methyl-5-triethylsilanyloxy-tetrahydro-pyran-3-yloxy)-6-methyl-3,5-bis-triethylsilanyloxy-tetrahydro-pyran-4-yl ester 
• 106711-65-3 Acetic acid (2S,3R,4S,5R,6R)-2-((2R,3R,4R,5R,6R)-4-acetoxy-2-formyloxy-6-methyl-5-triethylsilanyloxy-tetrahydro-pyran-3-yloxy)-6-methyl-3,5-bis-triethylsilanyloxy-tetrahydro-pyran-4-yl ester 

Downstream Products

• 63166-73-4 Phyllanthoside 

Relevant articles and documents

Phyllanthoside-Phyllanthostatin Synthetic Studies. 8. Total Synthesis of (+)-Phyllanthoside. Development of the Mitsunobu Glycosyl Ester Protocol

The first total syntheses of the antineoplastic glycoside (+)-phyllanthoside (1) and the parent disaccharide (-)-phyllanthose (5) have been achieved. Stereoselective Koenigs-Knorr coupling of two 6-deoxyglucose derivatives, bromide 54 and alcohol 55, generated the uncommon 1′ → 2β glycosidic linkage of (-)-phyllanthose. A stereochemically convergent Mitsunobu reaction of protected disaccharide 87 with aglycon carboxylic acid 80, prepared via asymmetric synthesis, then led to 1 of high enantiomeric purity. The Mitsunobu procedure comprises an efficient general method for stereospecific assembly of β-glycosyl esters.

Phyllanthoside-Phyllanthostatin Synthetic Studies. 9. Total Syntheses of (-)-Phyllanthostatin 1, (+)-Phyllanthostatin 2, and (+)-Phyllanthostatin 3

Phyllanthostatins 1, 2, and 3 (2-4) have been synthesized for the first time. The unusual 1′→2β glycosidic linkages of the disaccharide moieties were constructed via anchimerically-assisted Koenigs-Knorr reactions. The novel β-glycosyl esters were then ge