1067175-36-3 Usage
Uses
Used in Catalyst Industry:
2-(Dicyclohexylphosphino)-N,N-bis(1-Methylethyl)-1H-indole-1-carboxaMide, Min. 98% AMidole-Phos is used as a phosphine ligand for the synthesis of transition metal complexes, which are essential catalysts in various chemical reactions. Its unique structure provides enhanced stability and selectivity, making it a valuable component in the development of efficient and sustainable catalytic systems.
Used in Asymmetric Catalysis:
In the field of asymmetric catalysis, 2-(Dicyclohexylphosphino)-N,N-bis(1-Methylethyl)-1H-indole-1-carboxaMide, Min. 98% AMidole-Phos is used as a chiral ligand to induce enantioselectivity in catalytic reactions. Its structural features enable the creation of metal complexes with high enantiomeric excess, which is crucial for the production of optically active compounds in the pharmaceutical and agrochemical industries.
Used in Hydrogenation Reactions:
2-(Dicyclohexylphosphino)-N,N-bis(1-Methylethyl)-1H-indole-1-carboxaMide, Min. 98% AMidole-Phos is employed as a ligand in hydrogenation reactions, particularly for the selective hydrogenation of polyolefins. The supported rhodium catalyst, which incorporates this ligand, exhibits similar selectivity to its homogeneous counterpart, with negligible rhodium leaching, making it an environmentally friendly and cost-effective option for industrial applications.
Used in Cross-Coupling Reactions:
In the field of organic synthesis, 2-(Dicyclohexylphosphino)-N,N-bis(1-Methylethyl)-1H-indole-1-carboxaMide, Min. 98% AMidole-Phos is utilized as a ligand in cross-coupling reactions, such as Suzuki-Miyaura, Heck, and Sonogashira reactions. Its unique structure facilitates the formation of carbon-carbon and carbon-heteroatom bonds, which are essential for the synthesis of complex organic molecules and pharmaceuticals.
Used in Polymer Industry:
2-(Dicyclohexylphosphino)-N,N-bis(1-Methylethyl)-1H-indole-1-carboxaMide, Min. 98% AMidole-Phos is used as a ligand in the polymerization of olefins and other monomers. The resulting metal complexes exhibit high activity and selectivity, leading to the production of polymers with controlled molecular weights and architectures. This is particularly important in the development of advanced materials with tailored properties for various applications, such as automotive, electronics, and packaging industries.
Reactions
Suzuki-Miyaura Coupling of Aryl Chlorides (low catalyst loading).
Check Digit Verification of cas no
The CAS Registry Mumber 1067175-36-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,7,1,7 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1067175-36:
(9*1)+(8*0)+(7*6)+(6*7)+(5*1)+(4*7)+(3*5)+(2*3)+(1*6)=153
153 % 10 = 3
So 1067175-36-3 is a valid CAS Registry Number.
1067175-36-3Relevant academic research and scientific papers
A new family of tunable indolylphosphine ligands by one-pot assembly and their applications in Suzuki-Miyaura coupling of aryl chlorides
Chau, Ming So,Chung, Chiu Yeung,Chak, Po Lau,Fuk, Yee Kwong
, p. 7803 - 7806 (2008/12/22)
(Chemical Equation Presented) This study describes a new class of indolylphosphine ligands, which can be easily accessed by a simple one-pot assembly from commercially available indoles, acid chlorides, and chlorophosphines. A combination of these three starting materials provides a high diversification of the ligand structure. The application of this ligand array in palladium-catalyzed Suzuki-Miyaura coupling reaction of aryl chlorides with arylboronic acids is described. A catalyst loading down to 0.01 mol % of Pd can be achieved.
