1067175-44-3Relevant academic research and scientific papers
A new family of tunable indolylphosphine ligands by one-pot assembly and their applications in Suzuki-Miyaura coupling of aryl chlorides
Chau, Ming So,Chung, Chiu Yeung,Chak, Po Lau,Fuk, Yee Kwong
, p. 7803 - 7806 (2008/12/22)
(Chemical Equation Presented) This study describes a new class of indolylphosphine ligands, which can be easily accessed by a simple one-pot assembly from commercially available indoles, acid chlorides, and chlorophosphines. A combination of these three starting materials provides a high diversification of the ligand structure. The application of this ligand array in palladium-catalyzed Suzuki-Miyaura coupling reaction of aryl chlorides with arylboronic acids is described. A catalyst loading down to 0.01 mol % of Pd can be achieved.
