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1067198-74-6

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1067198-74-6 Usage

General Description

Icariin derivatives are a set of unique chemical compounds derived from icariin, a flavonoid plant extract found primarily in the herb Epimedium, commonly known as Horny Goat Weed. These derivatives are known for their various bioactive properties and have been widely studied for their potential medical and therapeutic applications. Some primary uses include enhancing sexual performance, combating erectile dysfunction, and promoting bone health. They also demonstrate potential in the fields of neuroprotection, anti-inflammatory, cardiovascular protection, anti-osteoporosis, and anti-tumor activities. However, the potential side effects and exact mechanisms of actions are still under active research. Validation through clinical trials is necessary to confirm these benefits and to assess for safety and dosage parameters.

Check Digit Verification of cas no

The CAS Registry Mumber 1067198-74-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,7,1,9 and 8 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1067198-74:
(9*1)+(8*0)+(7*6)+(6*7)+(5*1)+(4*9)+(3*8)+(2*7)+(1*4)=176
176 % 10 = 6
So 1067198-74-6 is a valid CAS Registry Number.

1067198-74-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-hydroxy-3,7-bis(2-hydroxyethoxy)-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one

1.2 Other means of identification

Product number -
Other names 3,7-bis-(2-hydroxyethyl)icaritin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1067198-74-6 SDS

1067198-74-6Downstream Products

1067198-74-6Relevant articles and documents

3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats

Lan, Tao-Hua,Chen, Xiao-Ling,Wu, Yun-Shan,Qiu, Hui-Liang,Li, Jun-Zhe,Ruan, Xin-Min,Xu, Dan-Ping,Lin, Dong-Qun

, p. 102 - 111 (2018)

Pulmonary arterial hypertension (PAH) is a chronic progressive disease which leads to elevated pulmonary arterial pressure and right heart failure. 3,7-Bis(2-hydroxyethyl)icaritin (ICT), an icariin derivatives, was reported to have potent inhibitory activ

Icaritin (ICT) derivative and preparation method and application thereof

-

Paragraph 0035-0039, (2019/11/04)

The invention belongs to the field of pharmaceutical chemistry, and particularly relates to an icaritin (ICT) derivative shown as the formula (II), a pharmacologically-allowable salt and preparation method of the ICT derivative, and application of the ICT

Herba Epimedii glycoside compound and use thereof

-

Paragraph 0218; 0219; 0220; 0221; 0222, (2017/08/24)

The invention relates to an icariin compound and an application of the icariin compound in preparing medicines for preventing and treating fracture and osteoporosis. Particularly, the invention relates to the compound shown in a general formula (I) in the specification, a stereisomer, a stereomer, a tautomer, oxynitrides, hydrates, solvates, metabolites, and pharmaceutically acceptable salts or prodrugs thereof, wherein the variables are defined in the specification. The invention further relates to use of the compound, the stereisomer, the stereomer, the tautomer, oxynitrides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or salt of prodrugs thereof as medicines, particularly use in preparing medicines for preventing and treating fracture and osteoporosis.

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