106727-55-3

Upstream product

• 738-79-4 N-benzyl-3-benzylamino-2-butenamide 
• 106727-60-0 1-Benzyl-3-{1-[(E)-benzylimino]-ethyl}-4-hydroxy-1H-pyridin-2-one 

Downstream Products

• 108380-18-3 2-benzyl-4-(1-hydroxyethyl)-2-azabicyclo<2.2.0>hexane-3,5-dione 
• 108380-14-9 1-benzyl-3-(1-hydroxyethyl)-4-methoxy-2-pyridone 
• 108380-16-1 2-benzyl-4-(1-hydroxyethyl)-5-methoxy-2-azabicyclo<2.2.0>hex-5-en-3-one 
• 108380-12-7 3-acetyl-1-benzyl-4-methoxy-2-pyridone 

Relevant academic research and scientific papers

SYNTHESIS OF 1,3-DIOXIN-4-ONES AND THEIR USE IN SYNTHESIS. XI. 2,2-DIMETHYL-1,3-DIOXIN-4-ONE AS A SYNTHETIC EQUIVALENT OF FORMYLKETENE: SYNTHESIS OF HETEROCYCLIC COMPOUNS

Cycloaddition of formylketene generated in situ by thermolysis of 2,2-dimethyl-1,3-dioxin-4-one with N-benzhydrylidenebenzylamine yields 3-benzyl-2,2-diphenyl-1,3-oxazin-4-one.Analogous reactions with a carbodiimide, cyanamide, and keteneacetal afford the corresponding 4 + 2 cycloadducts.Reaction of formylketene with 3-amino-2-butenamides affords 4-hydroxy-2-pyridones having a C-2 unit at the 3-position.Keywords: 1,3-dioxin-4-one;formylketene; cycloaddition;1,3-oxazin-4-one; 4-pyrone; 3-acetyl-4-hydroxy-2-pyridone; thermolysis; uracil derivative.