106749-29-5

Basic information

• Product Name: (R)-ALPHA-AMINO-9-ANTHRACENEPROPANOIC ACID METHYL ESTER HYDROCHLORIDE
• Synonyms: (R)-ALPHA-AMINO-9-ANTHRACENEPROPANOIC ACID METHYL ESTER HYDROCHLORIDE
• CAS NO: 106749-29-5
• Molecular Formula: C18H17NO2.ClH
• Molecular Weight: 315.798
• Mol File: 106749-29-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-ALPHA-AMINO-9-ANTHRACENEPROPANOIC ACID METHYL ESTER HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-ALPHA-AMINO-9-ANTHRACENEPROPANOIC ACID METHYL ESTER HYDROCHLORIDE(106749-29-5)
• EPA Substance Registry System: (R)-ALPHA-AMINO-9-ANTHRACENEPROPANOIC ACID METHYL ESTER HYDROCHLORIDE(106749-29-5)

Safety Data

• Hazardous Substances Data: 106749-29-5(Hazardous Substances Data)

Usage

General Description

(R)-Alpha-amino-9-anthracenepropionic acid methyl ester hydrochloride is a chemical compound that is commonly used in the synthesis of organic materials and pharmaceuticals. It is a derivative of anthracene, a fused polycyclic aromatic hydrocarbon, and it contains an alpha-amino group and a propionic acid moiety. The hydrochloride salt form of this compound is often used to improve solubility and stability in water-based solutions. This chemical may have potential applications in the development of new drugs, dyes, and other organic compounds due to its unique structure and properties.

Upstream product

• 1588924-76-8 C₂₃H₂₅NO₄ 

Relevant articles and documents

Asymmetric fluorination of α-branched cyclohexanones enabled by a combination of chiral anion phase-transfer catalysis and enamine catalysis using protected amino acids

We report a study involving the successful merger of two separate chiral catalytic cycles: a chiral anion phase-transfer catalysis cycle to activate Selectfluor and an enamine activation cycle, using a protected amino acid as organocatalyst. We have demonstrated the viability of this approach with the direct asymmetric fluorination of α-substituted cyclohexanones to generate quaternary fluorine-containing stereocenters. With these two chiral catalytic cycles operating together in a matched sense, high enantioselectivites can be achieved, and we envisage that this dual catalysis method has the potential to be more broadly applicable, given the breadth of enamine catalysis. It also represents a rare example of chiral enamine catalysis operating successfully on α-branched ketones, substrates commonly inert to this activation mode.