1067530-19-1 Usage
Uses
Used in Pharmaceutical Industry:
5-(Methylsulfonyl)pyridin-3-amine is used as a potential therapeutic agent for its possible medicinal properties. The structural features of MSAPA suggest that it may have applications in the development of new drugs, although further research is required to explore its full potential, understand its mechanism of action, and assess its safety and efficacy.
Given the current state of knowledge, the specific applications of MSAPA in the pharmaceutical industry are not clearly defined. However, its unique structure may allow it to interact with biological targets in ways that could be leveraged for therapeutic benefit. This could include roles in the development of drugs for various diseases, depending on the outcomes of future research.
Further investigation is necessary to determine the exact applications and benefits of 5-(Methylsulfonyl)pyridin-3-amine, as well as to evaluate any potential risks associated with its use. As research progresses, more detailed applications may be identified, allowing for a clearer understanding of how MSAPA can be utilized in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 1067530-19-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,7,5,3 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1067530-19:
(9*1)+(8*0)+(7*6)+(6*7)+(5*5)+(4*3)+(3*0)+(2*1)+(1*9)=141
141 % 10 = 1
So 1067530-19-1 is a valid CAS Registry Number.
1067530-19-1Relevant articles and documents
Phosphoinositide-3-kinase inhibitors: Evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511
Lanman, Brian A.,Reed, Anthony B.,Cee, Victor J.,Hong, Fang-Tsao,Pettus, Liping H.,Wurz, Ryan P.,Andrews, Kristin L.,Jiang, Jian,McCarter, John D.,Mullady, Erin L.,San Miguel, Tisha,Subramanian, Raju,Wang, Ling,Whittington, Douglas A.,Wu, Tian,Zalameda, Leeanne,Zhang, Nancy,Tasker, Andrew S.,Hughes, Paul E.,Norman, Mark H.
supporting information, p. 5630 - 5634 (2015/01/08)
Replacement of the piperazine sulfonamide portion of the PI3Kα inhibitor AMG 511 (1) with a range of aliphatic alcohols led to the identification of a truncated gem-dimethylbenzylic alcohol analog, 2-(5-(4-amino-6-methyl-1,3,5-triazin-2-yl)-6-((5-fluoro-6-methoxypyridin-3-yl)amino)pyridin-3-yl)propan-2-ol (7). This compound possessed good in vitro efficacy and pharmacokinetic parameters and demonstrated an EC50 of 239 ng/mL in a mouse liver pharmacodynamic model measuring the inhibition of hepatocyte growth factor (HGF)-induced Akt Ser473 phosphorylation in CD1 nude mice 6 h post-oral dosing.
AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
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Page/Page column 63-64, (2009/05/28)
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the t
