106757-56-6

Basic information

• Product Name: (Z)-(-)-methyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate
• Synonyms: (Z)-(-)-methyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate
• CAS NO: 106757-56-6
• Molecular Weight: 186.208
• Mol File: 106757-56-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (Z)-(-)-methyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(-)-methyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate(106757-56-6)
• EPA Substance Registry System: (Z)-(-)-methyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate(106757-56-6)

Safety Data

• Hazardous Substances Data: 106757-56-6(Hazardous Substances Data)

Upstream product

• 91274-05-4 (2S,3S)-1,2-O-isopropylidene-1,2,3,4-tetrol 
• 15042-01-0 5,6-O-isopropylidene-L-ascorbic acid 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 14347-78-5 1,2-O-isopropylidene-D-glycerol 
• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 1779-58-4 (methyloxycarbonylmethyl)triphenylphosphonium bromide 

Downstream Products

• 847800-67-3 (R)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-(dimethyl-phenyl-silanyl)-propionic acid methyl ester 
• 847800-66-2 (S)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-(dimethyl-phenyl-silanyl)-propionic acid methyl ester 
• 115473-63-7 (5S,8S,8aS)-2-(3,8-dimethyl-2-oxo-1,2,4,5,6,7,8,8a-octahydroazulen-5-yl)acrylic acid 
• 168300-55-8 [(1R,2S)-2-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-cyclopropyl]-carbamic acid benzyl ester 
• 202392-39-0 ((2R,3R,5R)-5-Allyl-3-methyl-tetrahydro-furan-2-ylmethoxy)-tert-butyl-diphenyl-silane 
• 110098-09-4 (4R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-methyl-dihydro-furan-2-one 
• 110171-24-9 (R)-(+)-5-(tert-butyldiphenylsilanyloxymethyl)furan-2(5H)-one 
• 202392-41-4 tert-Butyl-[(2R,3R,5R)-5-(3-methoxymethoxy-propyl)-3-methyl-tetrahydro-furan-2-ylmethoxy]-diphenyl-silane 
• 202392-40-3 3-[(2R,4R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-methyl-tetrahydro-furan-2-yl]-propan-1-ol 
• 180187-77-3 (1R,2S,4R)-1-<<(tert-butyldiphenylsilyl)oxy>methyl>-2-(2,2-dimethyl-1,3-dioxolan-4-yl)cyclopropane 
• 112837-17-9 (R)-(+)-5-(hydroxymethyl)furan-2(5H)-one 

Relevant articles and documents

Synthesis of key fragments of amphidinolide Q - A cytotoxic 12-membered macrolide

β-Hydroxy aldehyde and alkyl ketone moieties were effectively synthesized as key intermediates of amphidinolide Q, a cytotoxic macrolide from the cultured dinoflagellate Amphidinium sp.. The asymmetric center of the former derivative was produced by Sharpless asymmetric epoxidation, followed by E-selective 1,4-addition to give the sp2 methyl group. Derivatization of the L-ascorbic acid derivative by Evans asymmetric alkylation and Peterson olefination provided the latter intermediate. The coupling reaction of the segments was examined.

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Oxidation method for primary or secondary alcohols

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