106762-46-3Relevant articles and documents
Directed Metalation of Pyridinesulphonamides. Synthesis of Pyridine-fused Isothiazoles and 1,2-Oxathioles
Alo, Babajide I.,Familoni, Oluwole B.,Marsais, Francis,Queguiner, Guy
, p. 61 - 64 (2007/10/02)
4-Lithio-N-t-butylpyridine-3-sulphonamide reacted with benzophenone and carbon dioxide respectively to give the corresponding intermediates which on appropriate treatment gave isothiazolo-3-one 1,1-dioxides.Metalation of 2- and 4-(N,N-dialkylaminosulphonyl)pyridines with lithium diisopropylamide (LDA) gave anions which reacted with benzophenone to give carbinols which thermally cyclised to 1,2-oxathiolopyridine and 1,2-oxathiolopyridine respectively.