106762-89-4

Basic information

• Product Name: (+/-)-5-amino-3,6-dihydro-3-<(1α,2β,4α)-2-hydroxy-4-(hydroxymethyl)cyclopentyl>-7H-1,2,3-triazolo<4,5-d>pyrimidin-7-one
• CAS NO: 106762-89-4
• Molecular Weight: 266.26
• Mol File: 106762-89-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-5-amino-3,6-dihydro-3-<(1α,2β,4α)-2-hydroxy-4-(hydroxymethyl)cyclopentyl>-7H-1,2,3-triazolo<4,5-d>pyrimidin-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-5-amino-3,6-dihydro-3-<(1α,2β,4α)-2-hydroxy-4-(hydroxymethyl)cyclopentyl>-7H-1,2,3-triazolo<4,5-d>pyrimidin-7-one(106762-89-4)
• EPA Substance Registry System: (+/-)-5-amino-3,6-dihydro-3-<(1α,2β,4α)-2-hydroxy-4-(hydroxymethyl)cyclopentyl>-7H-1,2,3-triazolo<4,5-d>pyrimidin-7-one(106762-89-4)

Safety Data

• Hazardous Substances Data: 106762-89-4(Hazardous Substances Data)

Upstream product

• 106762-84-9 (1R,2R,4S)-2-[2-Amino-6-chloro-5-(4-chloro-phenylazo)-pyrimidin-4-ylamino]-4-hydroxymethyl-cyclopentanol 
• 106762-83-8 (+/-)-(1α,3α,4β)-3-<(2-amino-6-chloro-4-pyrimidinyl)amino>-4-hydroxycyclopentamethanol 
• 106762-85-0 (+/-)-(1α,3α,4β)-3-<(2,5-diamino-6-chloro-4-pyrimidinyl)amino>-4-hydroxycyclopentanemethanol 
• 68715-64-0 (+/-)-(1α,3α,4β)-3-amino-4-hydroxycyclopentanemethanol 
• 106762-87-2 (+/-)-(1α,3α,4β)-3-(5-amino-7-chloro-3H-1,2,3-triazolo<4,5-d>pyrimidin-3-yl)-4-hydroxycyclopentanemethanol 

Relevant articles and documents

Synthesis and Antiviral Evaluation of Carboxylic Analogues of 2-Amino-6-substituted-purine 3'-Deoxyribofuranosides

Carbocyclic analogues of 2-amino-6-substituted-purine 3'-deoxyribofuranosides were synthesized by beginning with (+/-)-(1α,3α,4β)-3-amino-4-hydroxycyclopentanemethanol and 2-amino-4,6-dichloropyrimidine.The route parallels the earlier syntheses of the corresponding ribofuranoside and 2'-deoxyribofuranoside analogues.The 2-amino-6-chloropurine, guanine, and 2,6-diaminopurine derivatives and the analogous 8-azapurines were prepared.The analogue (3'-CDG) of 3'-deoxyguanosine is active in vitro against a strain of type 1 herpes simplex virus (HSV-1) that induces thymidine kinase and is modestly active against a thymidine kinase inducing strain of type 2-HSV. 3'-CDG is not active against a strain of HSV-1 that lacks the thymidine kinase inducing capacity, whereas the carbocyclic analogue of 2 amino-6-chloropurine 3'-deoxyribofuranoside is active against that strain.The carbocyclic analogue of 2,6-diaminopurine 3'-deoxyribofuranoside displayed modest activity in vitro against influenza virus.