1067647-43-1

Basic information

• Product Name: 1H-INDOLE-2,4-DIONE, 3-[2,5-DIHYDRO-3-METHYL-5-OXO-1-[4-(TRIFLUOROMETHOXY)PHENYL]-1H-PYRAZOL-4-YL]-3,5,6,7-TETRAHYDRO-6,6-DIMETHYL-1-PHENYL-3-(TRIFLUOROMETHYL)-
• Synonyms: 1H-INDOLE-2,4-DIONE, 3-[2,5-DIHYDRO-3-METHYL-5-OXO-1-[4-(TRIFLUOROMETHOXY)PHENYL]-1H-PYRAZOL-4-YL]-3,5,6,7-TETRAHYDRO-6,6-DIMETHYL-1-PHENYL-3-(TRIFLUOROMETHYL)-;6,6-Dimethyl-3-(5-methyl-3-oxo-2-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-pyr zol-4-yl)-1-phen;6,6-Dimethyl-3-(5-methyl-3-oxo-2-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-pyrzol-4-yl)-1-ph;6,6-Dimethyl-3-(5-methyl-3-oxo-2-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-pyrzol-4-yl)-1-phenyl-3-(trifluoromethyl)-6,7-dihydro-1H-indole-2,4(3H,5H)-dione
• CAS NO: 1067647-43-1
• Molecular Formula: C₂₈H₂₃F₆N₃O₄
• Molecular Weight: 579.4903392
• Mol File: 1067647-43-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-INDOLE-2,4-DIONE, 3-[2,5-DIHYDRO-3-METHYL-5-OXO-1-[4-(TRIFLUOROMETHOXY)PHENYL]-1H-PYRAZOL-4-YL]-3,5,6,7-TETRAHYDRO-6,6-DIMETHYL-1-PHENYL-3-(TRIFLUOROMETHYL)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDOLE-2,4-DIONE, 3-[2,5-DIHYDRO-3-METHYL-5-OXO-1-[4-(TRIFLUOROMETHOXY)PHENYL]-1H-PYRAZOL-4-YL]-3,5,6,7-TETRAHYDRO-6,6-DIMETHYL-1-PHENYL-3-(TRIFLUOROMETHYL)-(1067647-43-1)
• EPA Substance Registry System: 1H-INDOLE-2,4-DIONE, 3-[2,5-DIHYDRO-3-METHYL-5-OXO-1-[4-(TRIFLUOROMETHOXY)PHENYL]-1H-PYRAZOL-4-YL]-3,5,6,7-TETRAHYDRO-6,6-DIMETHYL-1-PHENYL-3-(TRIFLUOROMETHYL)-(1067647-43-1)

Safety Data

• Hazardous Substances Data: 1067647-43-1(Hazardous Substances Data)

Usage

General Description

1H-Indole-2,4-dione, 3-[2,5-dihydro-3-methyl-5-oxo-1-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-4-yl]-3,5,6,7-tetrahydro-6,6-dimethyl-1-phenyl-3-(trifluoromethyl)- is a complex chemical compound with a long name. It contains a 1H-indole-2,4-dione core, along with a 3-[2,5-dihydro-3-methyl-5-oxo-1-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-4-yl] side chain containing a tetrahydro and dimethyl group, as well as a phenyl and trifluoromethyl substituent. 1H-Indole-2,4-dione, 3-[2,5-dihydro-3-methyl-5-oxo-1-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-4-yl]-3,5,6,7-tetrahydro-6,6-dimethyl-1-phenyl-3-(trifluoromethyl)- may have potential applications in pharmaceuticals or chemical research due to its intricate structure and diverse functional groups.

Upstream product

• 1067647-93-1 2-[1,5-dihydro-3-methyl-5-oxo-1-(4-trifluoromethoxyphenyl)-4H-pyrazol-4-ylidene]-3,3,3-trifluoro-propanoic acid methyl ester 
• 18940-21-1 5,5-dimethyl-3-(phenylamino)cyclohex-2-en-1-one 

Relevant articles and documents

Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors

Novel indoledione derivatives were synthesized and evaluated as long chain fatty acid elongase 6 (ELOVL6) inhibitors. Systematic optimization of an indole class of lead 1 led to the identification of potent ELOVL6 selective inhibitors. Representative inhibitor 37 showed sustained plasma exposure and good liver penetrability in mice. After oral administration, 37 potently inhibited ELOVL6 activity in the liver in mice.