1067652-30-5

Basic information

• Product Name: (1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-2-[(S)-1-p-tolyl-ethylcarbamoyl]-cyclopentanecarboxylic acid methyl ester
• Synonyms: (1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-2-[(S)-1-p-tolyl-ethylcarbamoyl]-cyclopentanecarboxylic acid methyl ester
• CAS NO: 1067652-30-5
• Molecular Weight: 396.508
• Mol File: 1067652-30-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-2-[(S)-1-p-tolyl-ethylcarbamoyl]-cyclopentanecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-2-[(S)-1-p-tolyl-ethylcarbamoyl]-cyclopentanecarboxylic acid methyl ester(1067652-30-5)
• EPA Substance Registry System: (1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-2-[(S)-1-p-tolyl-ethylcarbamoyl]-cyclopentanecarboxylic acid methyl ester(1067652-30-5)

Safety Data

• Hazardous Substances Data: 1067652-30-5(Hazardous Substances Data)

Upstream product

• 1067652-68-9 C₁₀H₁₇NO₆S 
• 27298-98-2 (S)-1-(4-methylphenyl)ethylamine 

Relevant articles and documents

AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES

The invention provides compounds of the formula (I). N-oxides, addition salts, quaternary amines, metal complexes, stereochemically isomeric forms and metabolites thereof, wherein W is H,C 1-C 6 alkyl, C 3-C 6 cycloalkyl, aryl or heterocyclyl; Q is aryl or heterocyclyl; A is a five or six membered saturated, partially unsaturated or aromatic ring; D is (II) or (III) the other variables are as defined in the specification. The compounds of the invention are inhibitors of BACE and are among other things useful for the treatment and/or prevention of conditions associated with BACE activity such as Alzheimer's disease.